Ford Fusion is America’s most fuel-efficient midsize sedan for both hybrid and conventional gasoline models. The Fusion Hybrid with an EPA estimated 41 mpg rating in the city and 36 mpg on the highway tops the Toyota Camry hybrid by 8 mpg in the city and 2 mpg on the highway, while the four-cylinder Fusion with best-in-class highway fuel economy at 34 mpg tops the Toyota Camry four-cylinder by 2 mpg